When her father dies unexpectedly, Dr. Ayne Amjad is thrust to the helm of a decades-long struggle to aid Minden, a southern West Virginia town beset by cancer-causing chemicals. Haunted by her father’s mandate to “help others,” Ayne hatches an audacious plan to relocate the town and bring closure to her father’s work.

After encountering initial resistance, Ayne takes her ambitions statewide, landing a high-profile role as WV’s state health officer. But the demands of her new position combined with her goal of moving Minden take a dramatic toll on her health. When deeply entrenched community narratives collide with emerging scientific findings about the town’s pollutants, Ayne must decide how much she’s willing to sacrifice to help the people of Minden achieve their goals.